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The BIOFIRE System and Your Immune System

The BIOFIRE System provides syndromic infectious disease testing, empowering healthcare professionals to select the most appropriate test the first time. Patients benefit from quicker diagnosis and more targeted treatment. Clinicians benefit from better antibiotic stewardship. Labs improve efficiency and cost savings.

The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes, with semiquantitative results that take less than an hour.

Respiratory

The burning of biomass, such as plants, wood and other organic materials, produces gaseous pollution and fine particles that adversely affect the respiratory system. Additionally, the environmental issues caused by forest fires such as droughts, can be potentiated by climate change, which can increase their negative impacts on the human health.

In the United States wildfire smoke is associated with hospitalizations for respiratory illnesses like asthma, COPD, and lung cancer. Additionally, this kind of air pollution can be an underlying risk factor for cardiovascular diseases and a major contributor to the burden of disease among the most vulnerable populations, including people with lower socioeconomic status (SES).

During the COVID-19 pandemic, many communities were exposed to unhealthy levels of air pollution due to wildfires. The public health response has been limited to a public education campaign about managing symptoms. This knowledge gap is alarming due to the evidence of possible health risks resulting from the continual exposure to smoke and other sources of poor air quality.

Researchers are now evaluating the best way to safeguard public's health in the event of future events of this kind. NIH is funding research into this critical public health problem through the BLUE CORAL study as well as its successor, FIRE CORAL.

First time an prospective study will assess the long-term effects of exposure to smoke from wildfires or other sources. FIRE CORAL is a study that seeks adult participants who are hospitalized for COVID-19 index episode and who speak English or Spanish but aren't pregnant. The FIRE CORAL protocol includes a battery of tests conducted in-person, objectively measuring lung function tests and pulmonary imaging and functional assessments.

The lungs are especially sensitive to the effects of smoke and other particles due to the fact that they can trigger or exacerbate chronic respiratory illnesses, such as emphysema and COPD and increase the risk of pneumonia. A number of steps can be taken to prevent or lessen the negative health effects resulting from exposures to smoke, such as avoidance of outdoor activities whenever possible and using the EPA's "N95" mask, which is designed to trap fine particles.

Smoking can cause irritation to the eyes, throat and nose. To reduce the symptoms, drink lots of water and take medication to reduce inflammation, such corticosteroids.

Bloodstream

Your bloodstream is at the forefront of fighting germs that enter your body. Dendritic cells are specific cells, serve as a call center your fire department. They collect antigens from bacteria and release proteins to alert other white cells to fight. Circulating white blood cells, differentials, and band cells were increased during firefighters' firefighting shifts, and compared to levels after strenuous physical exertion without Bioethanol bio ethanol fire basket Bowl (Lesoutrali.Com)-fighting.

Skin

Dermatologists were concerned that smoke and ash from the California wildfires could cause negative effects on the skin of those exposed to the smoke and ash. Maria Wei, a graduate student at the University of California, Irvine is studying how severe pollution from wildfires affects the skin. Her research was published on April 22, 2012 in Scientific Reports.

Wei's research has shown that the temperature of a person's skin changes based on the length of time that the body is exposed to flames. It could take up to two hours for the skin of someone to reach their "flash point"--the point where it starts to burn and then turn into ash. It's crucial not to be near a fire pit or campfire, and you should always wear protective clothing if you're outdoors in a humid or hot day.

Forest fires will continue occur, despite the steps taken to stop wildfire pollution. Wei believes that as the climate changes cause forests to burn faster, the number of people who suffer from wildfires will increase. That means more people will have to wear long sleeves, hats, and thick moisturizers.

It's also worth knowing that the atopic dermatitis (itchy skin) that many people suffer from can be exacerbated by the air pollution from wildfires. The particles in smoke can clog pores, making atopic skin worse.

Another issue is that atopic dermatitis is known to make people more sensitive to UV light, which can be aggravated by wildfire smoke. This can cause people to be more likely to visit tanning salons and may cause them to tan with less protection than they need to.

A treatment with ice and fire may help reduce atopic skin conditions however, it isn't recommended for anyone with an open wound or rash. This treatment is not recommended for people with active acne or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial located at Novuskin Las Vegas' premier membership MedSpa is a result-driven, intensive facial that bridges between the mild facelift and the peel, but without the need for downtime. It is designed to resurface skin, reduce rosacea, decrease the appearance of acne scars and fine lines and also stimulate cellular regeneration. It's an incredible treatment that will give you radiant skin.

Infections

The human body is a complex system of organs and tissues that work together to protect us from infection. Infections are caused by microscopic organisms such as parasites, viruses, bacteria and fungus that invade healthy cells and cause them to reproduce beyond control. Your immune system could react by displaying signs of illness. These symptoms can be anything from a snoring nose to a stomach that is upset, but can also include swelling of lymph glands, or an scratch. The type of infection and its location can impact the symptoms.

Infections can spread in a variety of ways however the most common are from person to person through droplets that linger in the air after coughing or sneezing. Bacterial diseases like tuberculosis and strep throat meningococcal disease, and Legionnaires' disease spread in this manner, as do certain viral infections such as the common cold and influenza. Some bacteria-related infections, like skin infections and sexually transmitted infections (STIs) such as gonorrhea and Chlamydia, can be transmitted through contact with infected tissue or mucous membranes, or through indirect contact with surfaces that are contaminated. Certain infections caused by bacteria are transmitted by insects, such as ticks, fleas, or mosquitoes.

Viruses and some parasites are small enough to get into your bloodstream and infect your cells which can lead to serious diseases like the common cold and AIDS. Fungi can cause skin problems like ringworm and athlete's feet, while others infect the respiratory tract and nervous system.

The BioFire Panel utilizes our unique FilmArray technology to analyze the bronchoalveolar and sputum samples to determine a comprehensive list of pathogens that are involved in upper respiratory infection. The kit comes with a reagent kit that contains all the chemistry necessary to perform reverse transcription, nested multiplex PCR, and detection in one machine. It's a simple solution to aid clinicians in identifying and treat patients suffering from a variety of respiratory symptoms. The test has been granted an Emergency Use Authorization. It is available in bioMerieux CLIA medium and high-complex laboratories.