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Pragmatic trials are those that are designed to inform real-world clinical practice. They are usually focused on the practical aspects of the research design, like the recruitment and consent process as well as adherence to the use of standard equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and had participants from different geographical regions. This type of heterogeneity is required for pragmatic trials to be able to prove their validity and helps reduce bias in the results. A high degree of heterogeneity, however could cause issues with the trial design.

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Pragmatic Play has gained a reputation for offering high-quality games and a superior user experience. Its software can be used on mobile devices and in a variety of languages. It has established itself as one of the leading casino gaming platforms despite its relative youth. The latest releases include Wolves, a 5-reel video slot with a healthy RTP and impressive graphics. Other notable titles include Wolf Gold and Chilli Heat.

The purpose of pragmatic trials is to mimic real-life scenarios and gain maximum validity externally. They are typically requested by practitioners and policymakers to guide their decisions. They can be used to determine the causality of an intervention with its outcomes. However, they shouldn't be used to substitute for the use of explanation trials.

The pragmatism concept is controversial and there are doubts about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 made a distinction between explanatory studies, which prove the validity of a physiological or clinical hypothesis, as well as pragmatic trials that aid in policy and practice decision-making. They also suggested an approach to pragmatic trials, 프라그마틱 슬롯무료 which they called PRECIS.2 This tool sought to define the characteristics of a practical trial, including recruitment, design and delivery of the intervention, and the follow-up.

There is a growing trend in the number of pragmatic trials that have been published. A recent Medline query that used the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatism. It is important to note that the majority of these trials were conducted in primary care settings.