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Mesothelioma and Non Asbestos Exposure

The majority of mesothelioma cases occur on the lung linings as well as the abdomen. The rare cancer may also form in the linings of the heart or the testes (pericardium).

Asbestos exposure is a major risk factor for mesothelioma. However, some patients diagnosed with mesothelioma do not have a history of asbestos exposure.

Exposure to Asbestos

Asbestos is a natural mineral that was previously used in construction and industrial products worldwide. The workers in asbestos industries handled the material every day and were at risk of exposure. Asbestos particles can be trapped in the lungs, which can cause lung disease. This is referred to as asbestosis. As time passes, the asbestos fibers that are trapped in the lungs could cause mesothelioma. Asbestos can also be inhaled or ingested, and the risk of mesothelioma and other asbestos-related diseases increases with the amount and length of exposure.

Most cases of mesothelioma stem from occupational exposure. Asbestos was utilized in many trades, including construction, insulation and electrical work, as well as automobile maintenance and pipefitting. These trades are typically dominated by men and, as a result mesothelioma cases involving males comprise 75-80% of all reported cases. However, the phasing out of asbestos in the United States and other first-world countries has reduced exposure to asbestos on the job. This has led to a shift of cases as non-occupational asbestos exposure becoming more frequent.

Non-occupational mesothelioma can develop when asbestos is released from the workplace environment or found in the home or school environment. It can also be caused by exposure to secondhand asbestos litigation for example, when a family member is exposed to the clothes of an exposed asbestos worker. Those who experience this type of exposure may have symptoms like breathlessness or chest pain, which is commonly mistaken for lung or heart problems.

Some studies have linked mesothelioma with non-occupational exposure, however the results vary. Many of these studies have been conducted with a small sample size, and the between-study heterogeneity has been high. It is essential to conduct more research to establish the link between non-occupational asbestos exposure and mesothelioma.

People who have been exposed to non-occupational asbestos should discuss their asbestos background with their doctor. They should seek mesothelioma tests when they are concerned, and ask for a referral to an expert. Mesothelioma specialists are able to provide patients with the best care and treatment options to improve their odds of survival. They will look over medical records, and perform imaging tests to identify the disease. They will also give advice on how to file a mesothelioma suit to receive compensation from an asbestos trust fund.

Secondhand Exposure

While asbestos exposure is the primary cause of mesothelioma not the only reason to get this cancer. In fact, there is a small amount of evidence that suggests that people may develop mesothelioma even though they never directly handled asbestos or worked in an industry with asbestos lawsuit-related activities. This is known as secondary or non-occupational asbestos exposure.

Asbestos fibers are very small and can adhere to clothing, hair skin, and other surfaces. Workers may carry dangerous fibers in their work clothing home and transmit them to family members. These stray asbestos fibers can be swallowed or inhaled, leading to mesothelioma.

This mesothelioma type occurs more frequently in women and usually in the lungs. It can also affect the chest wall or abdomen. The most commonly reported symptoms is breathlessness (dyspnea) and it is often accompanied by other symptoms like fluid in the lungs or swelling in the scrotum.

Pleural mesothelioma is a name that is used to describe mesothelioma, which is found in the lungs. Peritoneal mesothelioma is the term used for mesothelioma which affects the stomach wall or chest wall. This kind of mesothelioma may cause a number of symptoms like abdominal pain, difficulty breathing, and constipation.

A number of studies have shown that even those who have no prior previous history of exposure to asbestos could develop mesothelioma due to exposure to asbestos through secondhand fibers. They usually lived with someone who was exposed to asbestos. They may have touched the garments of the worker, or they might have had other contact with asbestos.

Veterans are at a greater risk of mesothelioma because asbestos was widely used in military bases as well as vehicles and ships. The Navy is particularly at risk because asbestos was used to protect the hull of the ship and to fireproof gun turrets. Additionally, sailors often brought home asbestos from their jobs aboard ships that were contaminated by asbestos.

Environmental Exposure

Mesothelioma has been linked to a variety of substances. However, the condition is usually linked to exposure to asbestos. Asbestos is a naturally occurring mineral that was utilized for a number of years in manufacturing. The mineral is heat resistant and tough, which makes it ideal for insulation, brakes, shingles, flooring and other products. When asbestos is broken up it produces dust which can be inhaled or swallowed. The asbestos fibers can stay in the stomach or lungs for years, triggering mesothelioma symptoms.

The most frequent mesothelioma symptoms are chest pain as well as abdominal discomfort, and difficulty breathing. Asbestos sufferers may suffer from these symptoms for 20 to 60 years or more following their initial exposure. These symptoms could be mistaken for other ailments, so it is important to see a doctor if you have these symptoms. It is also critical to inform your doctor of your past history of asbestos. This will prevent a faulty diagnosis and ensure that you receive the correct treatment.

Mesothelioma resulting from exposure to asbestos is most prevalent in people who work directly with asbestos, but it can also affect loved relatives of those who have been exposed. This is referred to as secondary exposure. Family members may inhale or swallow asbestos fibers on the clothing of a worker, shoes or tools. They may be exposed to asbestos to asbestos by someone who brings home these particles on their hair or clothing. This is why mesothelioma patients and their families must be sure to clean their clothes properly after working with asbestos.

There is a substantial collection of studies that show a relationship between nonasbestos exposure and mesothelioma, but there are no definitive conclusions yet on the role of other agents. For instance, there is some evidence that the zeolites erionite and chlorosotile can cause mesothelioma. Erionite is found in soil and rocks in certain areas of Turkey where mesothelioma occurrence rates are high.

Research into the relationship between mesothelioma and nonasbestos exposure continues. Funnel plots suggest the possibility of publication bias and there is a large degree of variability between studies. However, it's evident that occupational exposure to asbestos is the most important risk factor for mesothelioma.

Genetics

Mesothelioma is a rare condition caused by malignant mesothelial cells which grow out of control and invade surrounding tissues. It can also expand throughout the body through traveling through the bloodstream or lymphatic system and impacting other organs. Although asbestos is the primary cause of mesothelioma is not the only risk factor. Other environmental and genetic factors can also trigger the condition.

In a few cases mesothelioma is seen in people who were not exposed to asbestos. These are referred to as non-occupational mesothelioma patients. They typically experienced an indirect exposure due to the handling of contaminated clothing or home items by an asbestos-exposed person in their home. For instance, it's possible for someone to be diagnosed with pleural mesothelioma as a result of the inhalation of asbestos fibers from a loved one's clothing. Studies have shown that these kinds of mesothelioma cases are more likely to have longer periods of latency and are more likely to be diagnosed in wives than in husbands.

Scientists are examining the possibility that genetic predispositions to mesothelioma may play a role in the development. Recent studies have demonstrated that the mutation of a gene called BAP1 increases the risk of mesothelioma in those who have been exposed to asbestos. This is particularly important, as it could be the basis for improved screening procedures for those who are at risk of developing mesothelioma.

Researchers have discovered that a number of genes are linked to mesothelioma. These genes are often mutated in mesothelioma and inhibit the growth of tumors. These genes include large tumor suppressor 2 (LATS2) and NF2.

People with mesothelioma in their family are at a higher risk of developing the disease. This is due to certain genes, like the BAP1 one, can be inherited from a parent. Asbestos was used heavily in the military for a number of years and veterans suffer from the highest mesothelioma rate when compared to other occupational categories. The people who served in the Navy and on ships specifically were at risk the most because of the extensive exposure to asbestos in insulation, fireproofing materials, and shipbuilding.